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Bioinformatics Scientist

Consult
locationBoston, MA, USA
PublishedPublished: 6/14/2022
Technology
Full Time

Job Description

Bioinformatics Scientist – Antibody Discovery


A growing global veterinary pharma organisation is seeking a Bioinformatics Scientist to support antibody discovery programmes across companion animals (dogs, cats, horses).


Key Responsibilities

  • Analyse NGS and genomic datasets to support antibody discovery and target validation
  • Work with antibody repertoire data (CDRs, frameworks, VH/VL)
  • Apply protein modelling and in silico antibody engineering (e.g. optimisation, liability assessment)
  • Support identification of genetic variation impacting therapeutic targets
  • Contribute to development of internal antibody data tools / databases
  • Collaborate closely with discovery biology and R&D teams


Key Requirements

  • Experience working with therapeutic antibodies (essential)
  • Experience with NGS data, ideally in an antibody/repertoire context
  • Understanding of antibody structure (CDRs, frameworks)
  • Background in bioinformatics / computational biology / structural biology
  • Familiarity with protein modelling tools (e.g. Rosetta, MOE or similar)


Please apply below or reach out directly for more information.

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