Job Description
Job DescriptionTitle: Associate Scientist II
Location: Watertown, MA
Duration: 1 year
Shift: onsite; Monday-Friday, 8am-5pm
Payrate: $44/hr. on W2
Top skills per mgr:
1. Technical skills (cell/molecular biology)
2. Attention to detail
3. Mammalian cell culture experience
4. Master's Degree + min of 2 years working experience preferred
Purpose:
- The Rare Disease Research team is looking for a highly motivated Associate Scientist I to support early-phase research aimed at developing Client therapies for patients with rare blood disease.
- The candidate will be responsible for cell and molecular biology work supporting in vitro and ex vivo studies to identify and validate new targets.
- The ideal candidate is a self-starter who is eager to learn, highly collaborative, and detail oriented.
- The successful candidate will be asked to carry out scientifically and technically rigorous experiments and analysis and will receive training and mentorship from multiple Scientists.
Essential Functions:
Laboratory Techniques:
- Mammalian cell culture (including isolation of hematopoietic cells from human bio samples, culture & differentiation of human primary hematopoietic cells, generation of edited lines via eg CRISPR/Cas or overexpression)
- Tissue sample processing (protein and mRNA) for downstream bioassays
- Generating and analyzing cell-based/molecular assay data using a variety of methodologies (examples: qRT-PCR, plate-based assays, enzyme assays) with rigorous scientific standards, troubleshooting where needed, and careful documentation practices
- Optimization and troubleshooting of bioassays
- Additional Responsibilities:
- Maintenance of electronic laboratory notebooks
- Maintenance and troubleshooting of lab instruments
- Data package preparation and presentation
- Participation in team meetings
Requirements:
- MS in biology + 2 years working experience (PREFERRED) or BA in biology + 4 years experience
- 2+ years of relevant laboratory experience (industry setting preferred, not academic)
- Hands-on experience with mammalian cell culture. (Preferred: experience with isolation and culture of primary human hematopoietic cells, experience generating edited cell lines)
- Experience in downstream bioassays including one or more of the following: qPCR, ELISA/Western blot, multicolor flow cytometry
- Practical knowledge in basic cell and molecular biology principles
- Able to work independently on tasks of moderate complexity with limited supervision; able to troubleshoot complex tasks
- Commitment to careful and thorough technical documentation, including electronic laboratory notebooks and study reports
- Strong organizational and communication skills, strong attention to detail
- Ability to multitask, prioritize, and make independent decisions about day-to-day activities.
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