Job Description
Seeking a Bench Scientist II to support discovery research activities, primarily focused on cell culture, molecular biology, and immunology-related laboratory work. This is a hands-on laboratory position supporting ongoing research programs.
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Location
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• Cambridge, MA (Kendall Square)
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• 100% Onsite
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Duration
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• Initial contract: 12 months
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• Strong likelihood of extension for an additional year (up to 24 months total)
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Required Qualifications
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Candidates should have experience in a laboratory setting with:
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• Cell culture
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• Molecular biology techniques
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• Immunology-related research
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• Antibody-related assays/testing
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• General laboratory experimentation
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Animal Work
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Candidates do not need prior animal handling experience but must be:
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• Comfortable working with laboratory animals (primarily mice)
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• Comfortable with tissue collection/dissection
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• Open to learning animal handling procedures
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Training will be provided for:
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• Tissue isolation/dissection
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• Animal handling
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• Mouse dosing procedures (IP injections)
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Preferred Qualifications (Nice-to-Have)
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• Flow Cytometry
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• ELISA experience
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• Tissue processing experience
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• Animal dosing experience
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• Antibody characterization/testing
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Experience Requirements
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• Academic research experience is acceptable
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• Industry experience is not mandatory
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• Research technicians and laboratory personnel from universities, research institutes, biotech, or pharma environments are encouraged
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Target Candidate Profile
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Strong candidates may come from:
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• Pharmaceutical companies
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• Biotechnology companies
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• Academic research laboratories
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• Universities such as UMass, Boston University, and other research-focused institutions
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Candidates with backgrounds in:
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• Immunology
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• Cell Biology
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• Molecular Biology
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• Translational Research
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• Antibody Research
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Group is seeking a Senior Associate Scientist (contingent worker) to support antibody discovery projects focused on B cell-based workflows. This role will contribute to therapeutic antibody discovery campaigns using rodent immunization, serum titer screening, B cell sorting by flow cytometry, immune library generation, and hybridoma-based methods. The successful candidate will execute established laboratory workflows that support immunization-based discovery, including rodent selection, immunization strategies (protein, cell-based, and genetic), serum response evaluation by ELISA, flow cytometry, VH/VL molecular cloning, immune library generation and quality control, electrofusion, and hybridoma culture and screening. The role will also contribute to the evaluation and implementation of new technologies that enhance immunization and flow cytometry-based antibody discovery workflows in collaboration with other group members.
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The successful candidate should bring hands-on experience and technical capability in several of the following areas, aligned with the responsibilities of the role:
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Hands-on experience supporting antibody discovery workflows, including flow cytometry, B cell-based methods, or hybridoma-based screening.
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Working knowledge of molecular biology techniques such as PCR, cloning, and immune library generation or related sample preparation workflows.
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Experience with laboratory documentation, data organization, and communicating experimental results clearly to project teams.
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Strong laboratory organization skills, including reagent handling, inventory support, and maintaining materials needed for experimental workflows.
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Responsibilities:
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Provide laboratory support for therapeutic antibody discovery campaigns using flow cytometry, immune library generation, and hybridoma-based methods.
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Execute established workflows to support rodent immunization studies, serum titer screening, B cell sorting, molecular cloning, and related sample processing activities.
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Maintain reagent inventories, prepare laboratory materials, and ensure operational readiness for discovery activities.
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Document experimental procedures, results, and observations accurately in laboratory records and internal data systems.
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Summarize data and communicate key findings, experimental progress, and campaign outcomes to project teams.
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Nice-to-have skills:
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Experience with flow cytometry-based analysis or cell sorting.
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Experience with laboratory automation or high-throughput workflows.
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Experience working with rodents, particularly mice, in a research setting.
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Experience working with hybridoma generation, culture, or screening workflows.
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Qualifications:
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Bachelor’s degree in biology, immunology, molecular biology, biochemistry, or a related scientific discipline, with at least 2 years of full-time laboratory experience in an academic or industry setting.
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EEO:
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Mindlance is an Equal Opportunity Employer and does not discriminate in employment on the basis of – Minority/Gender/Disability/Religion/LGBTQI/Age/Veterans